一、基本信息
熊英，博士，副研究员，硕士生导师
电子邮件：ying.xiongAThubu.edu.cn
研究领域：脑功能和脑疾病，蛋白质组学
二、教育背景
2005 – 2012 中国科学院遗传与发育生物学研究所，博士
2001 – 2005 武汉大学，生物学基地班，学士
三、工作经历
2023 – 至今 必赢集团网站，副研究员
2021 – 2023 中国科学院遗传与发育生物学研究所，客座研究员
2016 – 2020 美国哈佛医学院波士顿儿童医院，博士后
2012 – 2015 中国科学院遗传与发育生物学研究所，博士后
四、科研项目
1. 武汉市重点研发计划项目“新型孤独症动物模型的构建和表型干预”，2024-2026，主持
2. 湖北省自然科学基金联合基金项目“基于时空蛋白质组解析父代肾虚影响仔鼠大脑皮质层发育的分子机制”，2025-2027，主持
3. 国家自然科学基金重大项目“孤独症风险基因跨物种动物模型的构建及表型鉴定”，2024-2028，参与
五、代表性论文
1. Huilin Hong, Chao Guo, Xueru Liu, Liguang Yang, Wei Ren, Hui Zhao, Yuan Li, Zhongyin Zhou, Sin Man Lam, Jidong Mi, Zhentao Zuo, Cirong Liu, Guo-Dong Wang, Yan Zhuo, Ya-ping Zhang, Yixue Li, Guanghou Shui, Yong Q. Zhang*, Ying Xiong*. Differential effects of social isolation on oligodendrocyte development in different brain regions: insights from a canine model. Front Cell Neurosci. 2023, 17:1201295
2. Huilin Hong, Zhiguang Zhao, Xiahe Huang, Chao Guo, Hui Zhao, Guo-Dong Wang, Ya-PingZhang, Jian-Ping Zhao, Jianhui Shi, Qing-Feng Wu, Yong-Hui Jiang, Yingchun Wang, Lei M Li, ZhuoDu, Yong Q Zhang*, Ying Xiong*. Comparative Proteome and Cis-Regulatory Element Analysis RevealsSpecific Molecular Pathways Conserved in Dog and Human Brains. Molecular & Cellular Proteomics. 2022, 21(8):100261
3. Ying Xiong, Huilin Hong, Cirong, Liu, Yong Q. Zhang. Social isolation and the brain: effects and mechanisms. Molecular Psychiatry. 2022, 28:191-201.
4. Guoli Zhao, Yingga Wu, Li Du, Whenua Li, Ying Xiong, Aiyu Yao, Qifu Wang, Yong Q. Zhang. Drosophila S6 kinase like inhibits neuromuscular junction growth by downregulating the BMPreceptor Thickveins. Plos Genetics. 2015, 11(3): e1004984
5. Chuan-Xi Mao, Ying Xiong, Zhaohuan Xiong, Qifu Wang, Yong Q. Zhang, Shan Jin. Microtubule-severing protein Katanin regulates neuromuscular junction development and dendriticelaboration in Drosophila. Development. 2014, 141(5): 1064-1074
6. Ying Xiong, Kai Zhao, Jiaxi Wu, Zhiheng Xu, Shan J, Yong Q. Zhang. HDAC6 mutationsrescue human tau-induced microtubule defects in Drosophila. Proceedings of the National Academyof Sciences. 2013, 110(12): 4604-9
7. Haiying Zhang, Ling Tian, Stephen Tobe, Ying Xiong, Songyan Wang, Xinda Lin, Yanan Liu, William Bendena, Sheng Li, and Yong Q. Zhang. Drosophila CG10527 mutants are resistant to juvenile hormone and its analog methoprene. Biochemical and Biophysical Research Communications, 2010, 401: 182-187.
